Anthocyanins, a group of natural flavonoids found in Korean black beans (also found in blue-, purple-, and red-colored fruits, flowers, and leaves) that regulate the PI3K/Akt/GSK3β pathways (Ali et al., 2018), have been reported to significantly reduce serum urate levels and XOD activity in the serum and livers of mice with yeast extract-induced hyperuricemia (Qian et al., 2019). Here, AKT1 is linked to hyperuricemia.