ABCG2 and hyperuricemia: Bergenin, a C-glucoside of 4-O-methyl gallic acid isolated from several medicinal plants, has been shown to reduce serum urate levels in a hyperuricemia-induced mouse model by elevating Abcg2 expression in both the kidney and intestine and by suppressing Slc2a9 expression in the kidney (Chen et al., 2020).