The neurofibromatosis type 2 (NF2) gene, a widely studied tumor suppressor gene, is an upstream regulatory gene of the Hippo pathway, and mutation of NF2 leads to a nonmalignant brain tumor syndrome called neurofibromatosis 2 (Yu et al., 2015; Dodson et al., 2019). Here, NF2 is linked to NF2-related schwannomatosis.