Quaking RNA-binding protein (QKI) regulates angiogenesis, embryogenesis, glial cell differentiation, apoptosis, and transcription, and it also regulates tumor cell metabolism, differentiation, proliferation, and immunity (Noveroske et al., 2002; Wu et al., 2002; Lee and Schedl, 2004; Larocque et al., 2005). This evidence concerns the gene QKI and neoplasm.