Other research has shown that transferrin (TF) and beta-1,4-N-acetyl-galactosaminyltransferase 1 (B4GALNT1) are highly expressed in patients with ccRCC, and B4GALNT1 may affect the occurrence and progression of renal cancer through the Hippo signaling pathway (Yang et al., 2019a). The gene discussed is TF; the disease is renal carcinoma.