SERPINE1 and gastric cancer: For example, researchers have found that lncRNA UBE2CP3 promotes the progression of GC by regulating the miR-138-5p/ITGA2 axis (31), and LncRNA NKX2-1-AS1 activates VEGFR-2 signal pathway by regulating miR-145-5p/SERPINE1 axis, which promotes angiogenesis and GC progression (32).