Namely, ZIKV infection was associated with a significant increase in the level of IFN-γ, a variable tendency to increase the levels of IFN-λ1 and IFN-λ2/3 without reaching statistical significance, but did not genuinely affect the level of either IFN-α or β (Figure 3D). This evidence concerns the gene IFNL2 and Zika virus infectious disease.