Additionally, in the descriptive statistics between subjects with severe cardiac changes and those with mild cardiac changes, the small LDL-P and cholesterol-depleted LDL (increase in the ratio LDL-TG/LDL-C) seemed to be the best differentiating ALT parameters, having also been found correlated with LV remodeling, systo-diastolic dysfunction, insulin resistance and inflammation. This evidence concerns the gene GPT and Insulin resistance.