Currently, by further analysis of 15 seed genes filtered out (IL1RN, GALNT12, ADH6, SCN7A, CXCL1, FGF18, SOX9, ACACB, PRRX1, MZB1, SLC22A3, CNNM4, LY6E, IFITM2, GDPD3), we discovered that IL1RN, ADH6, SCN7A, ACACB, MZB1, and GDPD3 were very limitedly studied in the context of CRC. The gene discussed is IL1RN; the disease is colorectal carcinoma.