For instance, Lang et al.'s (50) studies also found that joint action between VCM and HFD significantly enhanced liver disease and further resulted in some inflammatory foci and alterations of ALT and AST in circular blood, which were sufficient to exacerbate experimental NAFLD, as VCM did cause the liver to be more susceptible to damage from a secondary insult by decreasing mitochondrial function. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.