LTBP2 and primary congenital glaucoma: In previous studies, many mutation sites in LTBP2 have been proved to have some functions in the development of primary congenital glaucoma (c.3028G > A, p.Asp1010Asn; c.3427delC, p.Gln1143Argfs*35) (Rauf et al., 2020), cardiomyocytes (c.2206G > A, p.Asp736Asn) (Chen et al., 2020), and lung fibroblast-to-myofibroblast differentiation (Zou et al., 2021).