Some m6A methylation regulators (e.g., ALKBH5, HNRNPC, METTL14, YTHDF1, and YTHDF2) had significantly lower expression in AAA tissues than in normal aorta arteries, suggesting that imbalanced expression of m6A regulators plays a vital role in the formation and progression of AAA. The gene discussed is ALKBH5; the disease is triple-A syndrome.