RPL5 and acute lymphoblastic leukemia: In addition, different mutational studies performed in the last decade on pediatric T-ALL revealed a relatively high frequency (close to 10%) of somatic mutations in genes encoding for ribosomal proteins (RPs), namely ribosomal protein L5 (RPL5), RPL10 (de Keersmaecker et al., 2013), RPL11 (Tzoneva et al., 2013) and RPL22 (Rao et al., 2012), and these genes are recognized as potential T-ALL driver genes (de Keersmaecker et al., 2013; Liu et al., 2017).