CDK4 and clear cell renal carcinoma: For instance, the lncRNA DNA methylation-deregulated and RNA m6A reader-cooperating lncRNA (DMDRMR) interacts with the m6A reader insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) to stabilize target genes, like cyclin-dependent kinase 4 (CDK4), in an m6A-dependent manner, thus exerting an oncogenic effect in clear cell renal cell carcinoma (Gu et al., 2021).