IGHA1 and nephritis: The inheritance of the serum levels Gd-IgA1 has been established in familial and sporadic IgAN patients.[13] There is reported evidence that the aberrant IgA1 glycosylation is a frequently inherited defect, indicating a merging relation between the pathogenesis of Henoch-Schönlein purpura-induced nephritis and IgAN.[14]