These results were consistent with previous reports that age, anterior wall myocardial infarction, prolonged ischemia time, and NT-proBNP are predictors of AHF following STEMI.[14,22] Interestingly, the new findings in this study indicate that CA125 is also an independent predictor of AHF, suggesting that vigilance should be increased for subsequent AHF in STEMI patients with advanced age, longer total ischemia time, culprit vessel of LAD, elevated CA125 or/and NT-proBNP, and that timely intensive therapy is necessary. Here, NPPB is linked to anterolateral myocardial infarction.