In vitro experimental studies have found that MAPK/ERK activation of the PI3K/AKT signaling pathway can regulate VEGF family factors and affect the expression of cervical oncogenes, which may contribute to the development of cervical cancer.[30] The BACH1-IT1/miR-140-5p/VEGFA pathway axis, MAPK signaling pathway, and key factors VEGFA and FOS may be potential therapeutic targets in cervical intraepithelial neoplasia. The gene discussed is FOS; the disease is cervical intraepithelial neoplasia.