Namely, NE or ELA, was first discovered in 2005.[28] Then, Ki-67 markers were not found by immunohistochemical staining in ELA, which indicated maturation in the epithelium of gastric cancer after successful eradication.[32] Saka et al[31] further divided the proportion of ELA in cancerous areas into different grades and found that level 0 (≤ 10%) occurred more frequently in the control group. Here, MKI67 is linked to gastric cancer.