AKT1 and atherosclerosis: Moreover, the primary enriched pathways included cancer, lipid and atherosclerosis, PI3K-Akt and MAPK signaling pathways, advanced glycation endproducts-receptor for advanced glycation endproducts (AGE-RAGE) signaling in diabetes-associated complications, human cytomegalovirus, and hepatitis B, confirmed by enrichment analysis of overlapping targets of JHWD and PCOS-IR.