CCL2 and colorectal carcinoma: We detected increased secretion of cytokines reported to be promoters of CRC growth in vivo (CCL5 [32] and CCL2 [33]), poor prognostic biomarkers in CRC (CXCL10 [34], CCL2 [35]), promigratory factors (CXCL-12 [36]), and indicators of an immunosuppressive TME (CCL5 [37] and ICAM-1 [38]), along with cytokines with additional proangiogenic (ICAM-1 [38]) and macrophage recruitment potential (CCL2 [39] and CXCL10 [34]).