ICI-associated sialadenitis presents these clues: sicca syndrome is common (mouth 96%, eye 65%, abnormal unstimulated salivary flow 86%) and autoantibodies (ANA+ in 52%, anti-SSA in 20%, rheumatoid factor in 9%) are less common than in patients with pSS [28]. The gene discussed is BTG3; the disease is Sjogren syndrome.