In addition, the results of qRT-PCR displayed that in comparison to the adjacent tissues, LINC00460 expression was significantly up-regulated in tumor tissues (Fig. 1B, P < 0.01), and was also higher in lymph node metastasis of PC patients than that of non-metastasis patients (Fig. 1C, P < 0.01). This evidence concerns the gene LINC00460 and pachyonychia congenita.