Luteolin-mediated sensitization of cancer cells ameliorates the chemotherapy-induced cytotoxicity due to the downregulation and suppression of cellular pathways such as nuclear factor kappa B (NF-kB), phosphatidylinositol 3’-kinase (PI3K)/Akt, and X-linked inhibitor of apoptosis protein (XIAP) [6]. This evidence concerns the gene NFKB1 and cancer.