In concordance with the canine AD-associated PKP2 (plakophilin 2)-locus previously described by us12, the top 16th variant (effect size=6.8×10−5, chr27:16,009,789) in the BayesR analysis of GSD was located 14 kb upstream of the PKP2 gene. The gene discussed is PKP2; the disease is Alzheimer disease.