As depicted in Fig. 3a, the frequency of neonates with airway expression of FLG was reduced in the pre-infection samples from the RVI positive (55%) compared to the negative control (74%) group; the opposite occurred for TLR7, where higher rates of expression were found in the RVI positive pre-infection (71%) than in the negative control (37%) group. This evidence concerns the gene TLR7 and infection.