Compared to paracarcinoma tissues, carcinoma tissues had higher expression levels of CXCL9, CXCL10, CXCL11, CXCL13, CCL3, CCL4, CCL5 and LAMP3, resulting in higher TLS scores (p < 0.001) (Fig. 1E, Supplementary Fig. 2D). The gene discussed is CCL4; the disease is carcinoma.