CD274 and neoplasm: In this ICB-treated cohort, patients were categorized into two groups according to the PD-L1 expression in tumor biopsies, IC1(1 <  = PDL1 < 5%) and IC2/3 (PDL1 > 5%), with the finding that IC2/3 patients reached objective response rate (ORR) at 26% and CR rate at 11%, and a higher OS rate in CR/PR patients as compared with that of SD/PD patients.