We also performed further in-depth analyses to identify markers that were specifically expressed in tumor cells and found that 9 genes (COL4A6, LANCL2, PLA2R1, PLAC1, IL1A, MAGEA12, RNF128, GLI2 and DMP1) participated in the inhibition of TLS neogenesis, which deserved further molecular investigation. The gene discussed is MAGEA12; the disease is neoplasm.