There were no significant differences between groups in the mRNA levels of type III cell markers (Otop1, polycystic kidney disease-2L1 [PKD2L1], PKD1L3 and CA4), type II cell markers (T1R3 and gustducin), salty taste cell markers (ENaCα), and mature taste cell markers (Krt8) (P > 0.05, t-test; Fig. 6B, Table 6). This evidence concerns the gene KRT8 and polycystic kidney disease.