In the UCSC Xena database, compared with normal tissues, PAQR4 mRNA expression was significantly upregulated in 18 cancers, including BLCA, BRCA, CHOL, CAOD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, READ, STAD, THCA, UCEC, P-value <0.001; CESE, P-value <0.01; SARC, P-value <0.05 (Fig. 1A). Here, PAQR4 is linked to cancer.