MECP2 and Anxiety: In terms of variance, the final model accounted for 13.9% of the variance in anxiety symptoms and 7.3% of depressive symptoms, and these symptoms were predicted by the effects of the MECP2*gender interaction on childhood adversities (9.2%), suggesting that the relationship between childhood adversities and a symptom profile highly associated with risk of developing stress-related psychopathology is differentially marked by MECP2 in men and women.