VHL and oligoastrocytoma: Three out of the five VHL variants (Probands 9, 10 and 11; Table 1) have been described in association with von Hippel-Lindau syndrome and were classified as likely pathogenic or pathogenic, and the VHL-p.Arg210Trp variant (Proband 12; Table 1) was described in association with oligoastrocytoma and classified as likely pathogenic.