TET2 and acute myeloid leukemia: We also investigated 5′-Aza sensitivity in AML cell lines not derived from TET2-mutant disease, and although we observed sensitivity in THP-1 cells with TET2 knockdown, we did not see the same phenotype in KG-1 cells with TET2 knockout, which were relatively resistant to 5′-Aza compared with TET2 WT KG-1 cells.