A previous report demonestrated that Bach 1 knockdown controlled the progress of BLM-induced pulmonary fibrosis by controlling expressions of both Nrf2 and its downstream antioxidant elements as Ho-1 and Gpx1, so providing new insights into the role of Bach 1/Nrf2 in the control of oxidative stress involved in pathogenesis. This evidence concerns the gene NFE2L2 and pulmonary fibrosis.