TP53 and Lynch syndrome: Aligned with this observation, there are much more non‐penetrant, pathogenic variation in BRCA1/2 (0.2%–0.33%, 1/300–1/500),50 TP53 (0.2%, 1/500)30 and mismatch repair genes (Lynch syndrome; 0.23%,1/440)51 than previously expected.30