Information was missing for nearly all ACMG criteria except for likely pathogenic variants in KMT2C leading to an average AF for males of 2.64E‐06 and 2.06E‐06 for females along with one pathogenic frameshift variant for KMT2D (c.4168dup, p.Ala1390GlyfsTer42) one male allele (AF = 6.01E‐09) and none for females (Table 1). Here, KMT2D is linked to atrial fibrillation.