Baseline GPVI expression levels by flow cytometry and soluble GPVI levels were significantly lower among all the studied ITP patients compared with healthy controls; 1.86 ± 0.45 versus 4.8 ± 1.1 and 11 (8–18) ng/mL versus 82 (71–97) ng/mL, respectively; p = 0.001). This evidence concerns the gene GP6 and autoimmune thrombocytopenic purpura.