One important report illustrated that a complex formed by DEPDC1 and zinc finger protein 224 (ZNF224) can diminish the expression of zinc finger protein A20 to weaken the inhibitory effect of A20 on the degradation of the inhibitor of NF‐κB (I‐κB), thus promoting the translocation of NF‐κB into the nucleus to activate the expression of related genes, ultimately playing an anti‐apoptotic physiological role in bladder cancer.9 This evidence concerns the gene ZNF224 and urinary bladder cancer.