To explore the effect of Gal-9 or Tim-3 on mitochondrial dysfunction and oxidative stress in PD mice, we further examined the levels of H2O2 and malondialdehyde and the activity of endogenous antioxidant enzymes, including CAT and GPx, in the SN (Figures 4J–M). The gene discussed is HAVCR2; the disease is Parkinson disease.