Lnc-TALC, for example, was found to bind to miR-20b-3p in a competitive manner and thereby drive the expression of O6-methylguanine-DNA methyltransferase through c-Met pathway regulation [20], with the NEAT1 lncRNA that can regulate the let-7g-5p/MAP3K1 pathway to control the malignancy of glioblastoma stem cells and their ability to resist TMZ treatment [11]. The gene discussed is MAP3K1; the disease is glioblastoma.