IGF1 and glioblastoma: GBM patient tissues exhibited positive correlations between HOXA-AS2 and IGF1 levels (Figure 5(a)), and the knockdown of HOXA-AS2 in TMZ-resistant cell lines resulted in a corresponding drop in IGF1 expression at the mRNA and protein levels, while this was reversed by miR-302a-3p inhibitor treatment (Figures 5(b) and 5(c)).