They found that patients with stable cardiovascular disease and acute myocardial infarction had elevated serum MG53 levels (Xie et al., 2020a), and subsequent studies have shown that MG53 is a valuable prognostic indicator for patients with acute myocardial infarction (AMI) (Xie et al., 2020b), which can provide new ideas for clinical practice. This evidence concerns the gene TRIM72 and acute myocardial infarction.