Enriched pathway, in which the FOXO transcription factor family plays an important role in tumor proliferation and apoptosis [88], FOXO1 was shown to play a repressive role in hepatocellular carcinoma [89], and other FOXO transcription factors have been shown to be associated with hepatocellular carcinoma [90, 91]. The gene discussed is FOXO1; the disease is hepatocellular carcinoma.