ACHE and temporal lobe epilepsy: The BLA was chosen as the CNS site of interest because it receives dense cholinergic innervation, is rich in expression of AChE, is often a focal point for seizures in patients with temporal lobe epilepsy, and because it has been directly implicated in seizures as produced by OP-poisoning (Woolf and Butcher, 1982; Aroniadou-Anderjaska et al., 2008, 2009; Prager et al., 2013; Unal et al., 2015).