First of all, we investigated the relationship between the EXOC3L1 expression and OS in 33 cancers (Figure 3A), and the results pointed out that the aberrant expression of EXOC3L1 was correlated with OS in ACC (Figure 3B), KIRC (Figure 3C), LUSC (Figure 3D) and PAAD (Figure 3E), high expression of EXOC3LI was correlated with shorter OS in ACC and LUSC, whereas high expression of EXOC3L1 in KIRC and PAAD meant longer OS. This evidence concerns the gene EXOC3L1 and adrenal cortex carcinoma.