Various biomarkers of oxidative stress in T2DM include ROS, malondialdehyde (MDA), total cholesterol and reactive hydroperoxides (ROOH) (Sies and Jones, 2020), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR), and superoxide dismutase (SOD) (Couto et al., 2016; Dehdashtian et al., 2018). The gene discussed is GSR; the disease is type 2 diabetes mellitus.