TNF and amebiasis: In the UC samples, humoral immune response, neutrophil degranulation, neutrophil activation involved in immune response, antimicrobial humoral response, and granulocyte chemotaxis were the top five enriched BPs, while the IL-17 signaling pathway, amoebiasis, TNF signaling pathway, cytokine−cytokine receptor interaction, and complement and coagulation cascades were the top five enriched KEGG pathways.