In general, high YAP1 expression was risky in adrenocortical carcinoma (ACC), BLCA, COAD, brain lower grade glioma (LGG), LUAD, and pancreatic adenocarcinoma (PAAD), but it is a protective factor in esophageal carcinoma (ESCA), KIRC, PRAD, and mesothelioma (MESO) (Figures 3A, B). This evidence concerns the gene YAP1 and colon adenocarcinoma.