CD4 and cancer: In general, YAP1 expression was negatively correlated with the infiltration of CD8+ T cells, T follicular helper cells, γδ T cells, activated natural killer (NK) T cells, CD4+ Th1 cells, and myeloid dendritic cells in most cancer types, but positively correlated with the infiltration of MDSCs, cancer-associated fibroblasts (CAFs), and neutrophil cells (Figure 4A).