And taking the complete tumor set as a whole, we noticed that some genes, like SPP1, TNFRSF21 and BAX, were usually highly expressed in most tumors, while some in the bottom of this heatmap were mainly in relatively lower expression, represented by FGF10. Additionally, we performed uniCox analysis to explore the prognostic value of each gene on OS in 33 tumors (Figure 1C). The gene discussed is SPP1; the disease is neoplasm.