CXCR3 and cancer: CXCR3 was highly expressed in the cytoplasm and cytosol of cancer cells in patients with early breast cancer. This study showed that patients with high CXCR3 expression had shorter overall survival, and the expression level of CXCR3 was positively correlated with tumor size and the number of lymph nodes involved in metastasis, so high CXCR3 expression suggested a poorer prognosis for patients with early breast pain.