Our study showed that the length of hospitalization was longer and the incidence of preoperative jaundice, vascular invasion, lymph node metastasis, and elevated preoperative carcinoembryonic antigen and carbohydrate antigen 19-9 levels were more common in the iCCAphl patients than in the iCCApps patients. The gene discussed is CEACAM5; the disease is metastatic malignant neoplasm in the lymph nodes.