The subgroup analysis was also performed, which revealed that CDC20 upregulated expression was related to poor OS in non-small cell lung cancer (HR 2.40, 95% CI 1.91-3.02).<h4>Conclusions</h4>This meta-analysis demonstrated that highly expressing CDC20 was associated with poor survival in human malignancy tumors. This evidence concerns the gene CDC20 and non-small cell lung carcinoma.