WHO Grade 2 supratentorial glioma i) Diffuse astrocytoma (n = 25) ii) Oligoastrocytoma (n = 71) iii) Oligodendroglioma (n = 35) a) 1p19q co-deleted (n = 38 out of 119 tested) b) P53 over-expression (n = 65 out of 125 tested) c) IDH1 mutant (n = 107 out of 131 tested). The gene discussed is TP53; the disease is central nervous system cancer.