LRRK2 and Parkinson disease: Likewise, SNCA (α-synuclein), PARK2 (parkin), PARK7 (DJ-1), PINK1 and LRRK2 are the mutated genes of parkinsonism, among which mutations in both PARK2 (parkin) and LRRK2 are the most common genetic causes (Healy et al., 2008).