Furthermore, heterozygous missense SLIT2 variants were identified in three unrelated patients from a cohort with congenital anomalies of the kidney and urinary tract (CAKUT), one patient with bilateral subcortical renal cysts, one patient with right multicystic dysplastic kidneys, and one patient with right renal agenesis (Hwang et al., 2015). Here, SLIT2 is linked to congenital anomaly of kidney and urinary tract.