5'‐Ethynyl‐2'‐deoxyuridine (EdU) assay revealed that, compared with the negative control (NC) group, the EdU positive rate of the IRF8‐overexpressed group was significantly decreased in Molt4 and Jurkat cells, indicating that IRF8 slowed down the DNA replication rate in T‐ALL cells (Figure 1H). The gene discussed is IRF8; the disease is acute lymphoblastic leukemia.