LGALS4 and chronic pancreatitis: More detailed quantitative analysis of gal 4 in the mass spectrometry data set (22), comparing extracellular gal 4 protein levels between normal pancreatic tissue, chronic pancreatitis, PanIN (pancreatic intraepithelial neoplasia) precursor lesions, and PDAC showed increased gal 4 protein levels in the ECM with increased severity of lesions in both mouse and human tissue (Fig. 1B).